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Amifostine
- Article from:
-
Gale Encyclopedia of Cancer
- Author:
- Beaulieu, Nancy J
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Copyright informationCOPYRIGHT 2002 The Gale Group Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Amifostine
Definition
Amifostine, also known as the brand name Ethyol and as ethiofos or WR2721, is a medicine that helps protect certain tissues of the body from damage caused by
chemotherapy
or
radiation therapy
.
Purpose
Amifostine is a protectant agent that is used in combination with the chemotherapy drug
cisplatin
or in combination with radiation therapy. Amifostine is approved by the Food and Drug Administration (FDA) to prevent kidney damage caused by repeat doses of the chemotherapy agent cisplatin in patients who have a diagnosis of
ovarian cancer
or non-small cell lung cancer. It is also FDA approved for patients with head and neck cancer who are receiving ...
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