Article: Adenovirus Vectors Cannot Infect Female Germ-Line ...
Gene Therapy Weekly;  June 28, 2001 ;     700+ words ... ... staff medical writer - The risk of female germ-line infection with adenovirus during gene therapy is low, according to research in the United ... City, assessed this risk in female mouse germ-line cells and reported the findings in Molecular ...

Article: Mice produce transgenic progeny after in vivo germ ...
Gene Therapy Weekly;  December 16, 2004 ;     700+ words ... ... progeny after in vivo germ line stem cell transduction ... transduction of male germ line stem cells in vivo ... article was prepared by Gene Therapy Weekly editors from ... reports. Copyright 2004, Gene Therapy Weekly via NewsRx ...

Article: Gene Therapy
Gale Encyclopedia of Medicine, 3rd ed.;      700+ words ... ... a specific individual. Germ-line gene therapy inserts genes into reproductive ... disease. Others fear that germ-line gene therapy may be used to control ... basically two types of gene therapy. Germ-line gene therapy introduces ...

Article: FLI-1 Flightless-1 and LET-60 Ras control germ line ...
BMC Developmental Biology;  May 16, 2008 ;     700+ words ... ... elegans gonad is a bi-lobed organ composed of the germ line and somatic distal tip cells and sheath cells that partially envelop the germ line [1, 2]. The distal half of the germ line is a syncytium, with multiple germ nuclei sharing a ...

Article: Autosomal Genes of Autosomal/X-Linked Duplicated Gene Pairs and ...
Genetics;  March 1, 2005 ;     700+ words ... ... studies of three genes involved in early germ-line proliferation in Caenorhabditis elegans that lend unexpected insight into a germ-line/soma functional separation of autosomal ... gene pairs. In a genetic screen for germ-line proliferation-defective mutants, we ...

Article: Proteasomal Regulation of the Proliferation vs. Meiotic Entry ...
Genetics;  October 1, 2008 ;     700+ words ... ... number of cells that proliferate in the germ line and the number of cells that enter meiosis ... gametes. In the Caenorhabditis elegans germ line, the GLP-1/Notch signaling pathway ... proteasome, shifts this balance toward excess germ-line proliferation. We further demonstrate ...

Article: Prospects for gene therapy.
Chemistry and Industry;  September 16, 1991 ;     700+ words ... ... public concerns about gene therapy, mainly caused by ... between somatic and germ line therapy. The former ... gamete producing (germ line) cells of an individual ... routes to achieve gene therapy. However, germ line therapy in humans ...