Article: Philadelphia chromosome

Article: imatinib
A Dictionary of Nursing;      32 words ...imatinib (i- mat -i-nib) n. a cytotoxic drug used in the treatment of chronic myeloid leukaemia in which the Philadelphia chromosome is present and of gastrointestinal stromal tumours. Trade name: Glivec .

Article: CML
A Dictionary of Nursing;      9 words ...CML n. chronic myeloid leukaemia. See myeloid (leukaemia) .

Article: AML
A Dictionary of Nursing;      8 words ...AML n. acute myeloid leukaemia. See myeloid (leukaemia) .

Article: Subset of patients in early stage of CML respond well to ABMT, Italian researchers report.
Transplant News;  April 30, 1999 ;     227 words ......marrow transplantation utilizing Philadelphia chromosome-negative stem cells is well-tolerated...all cells were negative for the Philadelphia chromosome, and in all but 2 other cases...Regenerating marrow cells were [Philadelphia chromosome]-negative in 16 (53%) patients...

Article: amsacrine
A Dictionary of Nursing;      22 words ...amsacrine ( am -să-kreen) n. a cytotoxic drug administered by intravenous injection to treat acute myeloid leukaemia. Trade name: Amsidine .

Article: Blood Cancer Drug Discoveries: What The Future Holds.
Business Wire;  May 12, 2008 ;     503 words ......which, in the case of chronic myeloid leukaemia, has led to large increases...lumiliximab Revlimid Treanda Chronic myeloid leukaemia Gleevec Sprycel Tasigna bosutinib panobinostat Acute myeloid leukaemia Clolar Cloretazine Dacogen...

Article: myeloid
A Dictionary of Nursing;      71 words ......type of blood cell that proliferates abnormally originates in the blood-forming tissue of the bone marrow. See also Philadelphia chromosome . m. tissue a tissue in the bone marrow in which the various classes of blood cells are produced. See also haemopoiesis...

Article: translocation
A Dictionary of Nursing;      43 words ...translocation (tranz-loh- kay -shŏn) n. (in genetics) a type of chromosome mutation in which part of a chromosome is transferred to another part of the same chromosome or to a different chromosome. This can lead to serious genetic disorders, e.g. chronic myeloid leukaemia.

Article: Haematology.(Guest editorial)
CME: Your SA Journal of CPD;  June 1, 2007 ;     656 words ......mentioned in this journal--that of multiple myeloma and chronic myeloid leukaemia. Jackie Thomson discusses the modern management of multiple...in managing this disorder to all our population. Chronic myeloid leukaemia, discussed in the More About section, has also undergone...

Article: Pals' Kilimanjaro climb in memory of leukaemia victim.
Shields Gazette (South Shields, England);  July 11, 2008 ;     394 words ......Williams died just days after being diagnosed with acute myeloid leukaemia - a rare and aggressive form of cancer, which is most common...Sunderland Royal Hospital, a bone marrow biopsy confirmed acute myeloid leukaemia (AML) - a cancer of the blood-forming cells in bone marrow...

Article: busulfan
A Dictionary of Nursing;      41 words ...busulfan ( busulphan ) (bew- sul -fan) n. an alkylating agent that destroys cancer cells by acting on the bone marrow. It is administered by mouth or intravenous infusion, mainly in the treatment of chronic myeloid leukaemia. Trade names:. Busilvex ,. Myleran .

Article: FDA approves Gleevec for pediatric leukemia. (Updates).(Brief Article)
FDA Consumer;  July 1, 2003 ;     273 words ...Gleevec (imatinib mesylate) tablets were approved in May to treat children with Philadelphia chromosome positive chronic myeloid leukemia (CML)--a rare, life-threatening form of cancer that accounts for 2 percent of all leukemia in...

Article: Genentech focuses on cancer as it launches BioOncology initiative; new BioOncology initiative works to commercialize pipeline of biotherapeutic anti-cancer products.
Business Wire;  May 15, 1997 ;     675 words ......hairy-cell leukemia, AIDS-related Kaposi's sarcoma and Philadelphia Chromosome Positive chronic myelogenous leukemia. Genentech has...for alfa-2a, sarcoma modifier marketing recombinant) Philadelphia Chromosome Positive chronic myelogenous leukemia C2B8 antibody...

Article: hydroxycarbamide
A Dictionary of Nursing;      46 words ......hy-droks-i- kar -bă-myd) n. a drug that prevents cell growth and is administered by mouth mainly to treat chronic myeloid leukaemia. Hydroxycarbamide may lower the white cell content of the blood due to its effects on the bone marrow. Trade name: Hydrea...