Article: Could she be allergic to her work?

DEAR DR. DONOHUE: I don't know if you ever heard of this, but I hope you have. My doctor thinks I'm making it up. When I work - vacuum, clean, scrub floors - I start itching and break out with a rash on my face and chest. I am not making this up. I feel the itch, and I can see the rash. When I see the doctor, I don't have any symptoms. Do you have any idea what this might be? - R.M.

ANSWER: It could be cholinergic urticaria. The "cholinergic" part comes from acetylcholine, a chemical released by nerve cells. "Urticaria" is another word for hives.

Release of acetylcholine activates a special body cell, the mast cell, to release itch-causing, rash-provoking substances. Tiny, itchy hives pop ...

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