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Article: Peanut allergy vaccine may be close to testing in humans
- Article from:
- Chicago Sun-Times
- Article date:
- July 12, 2003
- Author:
CopyrightCopyright 2003 Chicago Sun-Times. (Hide copyright information)
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An experimental vaccine against peanut allergies that protected
mice from deadly reactions could begin human clinical tests in a year
or two, according to a report in the Journal of Allergy and Clinical
Immunology.
The vaccine was made from bacteria genetically engineered to
produce modified peanut proteins, then killed with heat treatment.
Given in suppository form, the three-dose vaccine turned off allergic
reactions in mice, which remained protected from a peanut challenge
three months later. Humans might need annual boosters, said Dr. Hugh
Sampson of Mount Sinai Medical School, who reported the advance with
colleagues in New York and at Arkansas Children's Hospital in Little
Rock.
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