Article: New AIDS Theory Devised on Computer

A typical AIDS investigator tests the power of experimental drugs or vaccines in a test tube, in chimps or even in human patients.

But Robert May and Martin Nowak of Oxford University are not typical AIDS researchers. They work on a desktop computer.

With that computer the two mathematical biologists have arrived at a remarkable new theory of how the human immunodeficiency virus, or HIV, causes AIDS.

Full-blown AIDS, they say, is not a gradual dismantling of a patient's immune system by HIV; it is a catastrophic event, triggered when the infecting virus diversifies into so many different strains that the immune system is suddenly overwhelmed.

It's not news that HIV diversifies. From ...

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