Article: AIDS Research Takes New Direction // Focus Turns From Virus to Immune System

After a long string of dismal results, AIDS research may finally be on a fruitful path, enlightened by a rapid-fire series of discoveries in recent weeks about the way the virus plunges the body's immune system into chaos.

"The history of this disease is a history of doorways never opened," said Dr. Joseph Sonnabend of the Manhattan-based Community Research Initiative on AIDS. "Finally, we are beginning to open the right doors."

Until recently, most research has focused on the human immunodeficiency virus and its ability to harm a component of the human immune system, called CD4 cells. But now a consensus is emerging that, from the earliest moments of infection, HIV tricks the immune ...

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