Article: Grapefruit juice may alter effects of drugs

In 1989, a group of Canadian researchers studying a blood pressure drug were astonished to discover that drinking a glass of grapefruit juice dangerously increased the drug's potency.

They were testing the effects of drinking alcohol on a medicine called Plendil. The scientists needed something that would hide the taste of alcohol so that subjects would know only that they were taking the drug and not know whether they were drinking alcohol with it.

"One Saturday night, my wife and I tested everything in the refrigerator," said Dr. David G. Bailey, a research scientist at the London Health Sciences Center in London, Ontario, and the lead author on the study. "The only thing that covered the ...

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