Article: PROBLEM CITED WITH PROMISING AIDS DRUG

STOCKHOLM - Some people infected with the deadly AIDS virus make antibodies against their own immune cells, which could render one of the most promising drugs under development useless, Harvard researcher William Haseltine said yesterday.

The surprise finding of these so-called autoantibodies, Haseltine said, may mean that the virus destroys the immune system indirectly as well as directly and has "serious implications" for the development of a new type of therapy against AIDS.

Working with a team of researchers from Boston's Dana-Farber Cancer Institute and New England Medical Center, Haseltine and coworker Joseph Sodroski found that about 10 percent of AIDS-infected people make ...

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