Article: Firms in `biochip' accord Genetics Institute, Affymetrix in joint quest for new drugs

Silicon Valley met Biotech Park yesterday as Cambridge-based Genetics Institute Inc. announced a collaborative agreement with Affymetrix Inc., of Santa Clara, Calif., to use "biochips" to help find new miracle drugs.

Biochips are dime-sized silica squares that can contain upward of 10,000 cells of DNA molecules -- 100 times more than conventional technology allows. The DNA, or gene fragments, are the protein building units that transmit hereditary characteristics.

Using light to create biochemical reactions for drug development and genetic analysis, these so-called DNA chips can speed up the scientific process of determining which fragments will bind or connect to a particular drug substance.

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