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Article: Mechanical Properties and Consequences of Stereocilia and Extracellular Links in Vestibular Hair Bundles
- Article from:
- Biophysical Journal
- Article date:
- April 15, 2006
- Author:
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Copyright informationCopyright Biophysical Society Apr 15, 2006. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
Although knowledge of the fine structure of vestibular hair bundles is increasing, the mechanical properties and functional significance of those structures remain unclear. In 2004, Bashtanov and colleagues reported the contribution of different extracellular links to bundle stiffness. We simulated Bashtanov's experimental protocol using a three-dimensional finite element bundle model with geometry measured from a typical striolar hair cell. Unlike any previous models, we separately consider two types of horizontal links: shaft links and upper lateral links. Our most important results are as follows. First, we identified the material properties required to match Bashtanov's ...
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