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Article: Complement components C2, C3, and C4 (C4A and C4B) and BF polymorphisms in populations of the Indian subcontinent
- Article from:
- Human Biology
- Article date:
- October 1, 1996
- Author:
CopyrightCopyright Wayne State University Press Oct 1996. Provided by ProQuest LLC. (Hide copyright information)
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A.H. AD'HIAH1'2 AND S.S. PAPIHA1
Abstract Genetic polymorphisms of the complement components (five loci: C2, C3, C4A, C4B, and BF) have been investigated in the Telugu-speaking Hindu population of Hyderabad, Andhra Pradesh, India, and the Bangali-speaking Muslim population of Dacca, Bangladesh. The available data are compared to understand the genetic variation of complement components in populations of the Indian subcontinent. The C3 *F and BF*F alleles show wide frequency variations in different ethnic groups of India. The range of variation in the C3*F allele is intermediate between European whites and southeast Asian populations, whereas the BF*F allele places the Indian frequencies ...