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Article: A Biopolymer Transistor: Electrical Amplification by Microtubules
- Article from:
- Biophysical Journal
- Article date:
- June 15, 2006
- Author:
CopyrightCopyright Biophysical Society Jun 15, 2006. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
Microtubules (MTs) are important cytoskeletal structures engaged in a number of specific cellular activities, including vesicular traffic, cell cyto-architecture and motility, cell division, and information processing within neuronal processes. MTs have also been implicated in higher neuronal functions, including memory and the emergence of "consciousness". How MTs handle and process electrical information, however, is heretofore unknown. Here we show new electrodynamic properties of MTs. Isolated, taxol-stabilized MTs behave as biomolecular transistors capable of amplifying electrical information. Electrical amplification by MTs can lead to the enhancement of dynamic information, ...
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