|
|
Article: Topical alprostadil (PGE^sub 1^) for the treatment of female sexual arousal disorder: In-clinic evaluation of safety and efficacy
- Article from:
- Journal of Psychosomatic Obstetrics and Gynecology
- Article date:
- March 1, 2006
- Author:
CopyrightCopyright Taylor & Francis Ltd. Mar 2006. Provided by ProQuest LLC. (Hide copyright information)
|
Abstract
This multi-center, randomized, placebo-controlled, crossover design study evaluated the effects of a topical alprostadil solution for the treatment of female sexual arousal disorder (FSAD). A total of 79 naturally or surgically post menopausal women with FSAD were treated with either 100 or 400 micrograms of alprostadil solution and placebo, delivered on separate clinic visits in random order. Study drug was applied to the external genitalia and was followed by 30 minutes of visual sexual stimulation. Study evaluations included investigator assessments of genital vasocongestion and patient assessments of physical and emotional sexual arousal, and sexual satisfaction. Genital ...