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Article: Specific IgE Antibodies Against Different Milk Allergens for in vitro Diagnosis of Cow's Milk Allergy
- Article from:
- Clinical Chemistry
- Article date:
- June 1, 2006
- Author:
CopyrightCopyright American Association for Clinical Chemistry Jun 2006. Provided by ProQuest LLC. (Hide copyright information)
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D-68
J. D. Faix. S. Johal, F. S. Mullins. Stanford University, Stanford, CA.
Serum-based immunoassays to measure specific IgE antibodies to allergens are useful ways to screen for allergy. Cow's milk is the most common food allergy, especially in patients less than 5 years of age. Most laboratories screen for specific IgE antibodies to cow's milk using an allergen preparation derived from whole milk (food allergen f2) but other PDA-approved milk-related allergens are also available for in vitro testing. The aqueous phase of whole milk includes micelles composed of casein proteins ("curd") and a protein-rich serum ("whey"). Individual allergen preparations available include casein (f78) as ...