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Article: Effect of Diacylglycerol on the Development of Impaired Glucose Tolerance in Sucrose-Fed Rats
- Article from:
- Lipids
- Article date:
- April 1, 2006
- Author:
CopyrightCopyright AOCS Press Apr 2006. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT: The effects of DAC oil and TAG oil on impaired glucose tolerance in rats that were fed a diet containing high levels of sucrose were compared. Male Wistar rats (8 wk old and 32 wk old) were fed either high-sucrose (57.5% sucrose w/w) or control diets containing either 10% (w/w) DAG or TAG oil with a similar FA composition for 48 wk in 8-wk-old rats and for 24 wk in 32-wk-old rats. Plasma lipids, the size of the islets of Langerhans, and insulin, glucose, and adipocytokine levels were measured. An oral glucose tolerance test (OGTT) was carried out during the study period. For rats in both age groups that were fed a high-sucrose diet, the DAG oil group had lower plasma glucose and ...