Article: Sleep disturbances, oxidative stress and cardiovascular risk parameters in postmenopausal women complaining of insomnia

ABSTRACT

Objective The aim of this work was to investigate cardiovascular risk factors and oxidative stress parameters as well as sleep disturbances in polysomnography recordings of 38 postmenopausal women with insomnia.

Methods Polysomnography recordings were performed on subjects for sleep analysis. Oxidative stress parameters were analyzed by measuring blood concentration of catalase, superoxide dismutase (SOD), thiobarbituric acid reactive substances (TBARS) and glutathione. For cardiovascular risk factors, we measured plasma levels of homocysteine, folic acid and vitamin B6.

Results Findings of polysomnography recordings revealed: 68% experienced decreased sleep efficiency, 50% had ...

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