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Article: Differences in insulin sensitivity in pregnant women with overweight and gestational diabetes mellitus
- Article from:
- Gynecological Endocrinology
- Article date:
- June 1, 2006
- Author:
CopyrightCopyright Taylor & Francis Ltd. Jun 2006. Provided by ProQuest LLC. (Hide copyright information)
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Abstract
Aim. The purpose of the present study was to investigate changes in insulin sensitivity using homeostasis model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI) in normal-weight and overweight women with normal glucose tolerance (NGT) and gestational diabetes mellitus (GDM) during pregnancy.
Methods. Ninety-two pregnant women in the first trimester, 202 in the second trimester and 154 in the third trimester were enrolled in this study. Fasting plasma glucose and insulin concentrations were measured in all women in the first, second and third trimesters. HOMA indices (insulin resistance, HOMA-IR and β-cell function, HOMA-β) and QUICKI were ...