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Article: Asymmetry of basal ganglia perfusion in Tourette's syndrome shown by technetium-99m-HMPAO SPECT
- Article from:
- The Journal of Nuclear Medicine
- Article date:
- February 1, 1997
- Author:
CopyrightCopyright Society of Nuclear Medicine Feb 1997. Provided by ProQuest LLC. (Hide copyright information)
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Our study involved performing brain perfusion SPECT scans on Tourette's subjects to observe any common perfusion abnormalities involving the cerebral cortex or subcortical structures. Method: Six patients with Tourette's syndrome and nine normal control subjects underwent a brain SPECT study with ^sup 99m^Tc-HMPAO. Regions of interest were generated over the cerebral cortex, basal ganglia, thalamus and cerebellum to evaluate any relative perfusion
abnormalities or asymmetry in the Tourette's subjects. Results: Five of the six Tourette's subjects demonstrated a significant decrease in right basal ganglia activity which was not present in any of the normal control subjects. Conclusion: Our ...