Article: Exercise-rest same-day SPECT sestamibi imaging to detect coronary artery disease

This study examined the results of exercise-rest same-day SPECT protocol in 193 patients, of whom 132 had coronary artery disease (CAD) by angiography (>=50% diameter stenosis), and 61 had a low pretest probability of CAD. Methods: The rest study was combined with first-pass radionuclide angiography using the multicrystal gamma camera in 72 patients. Results: The sensitivity of SPECT was 76% (25/33 patients) in patients with one-vessel, 84% in patients with two-vessel (38/45) and 98% in patients with threevessel CAD (53/54) (P = 0.01 versus one- or two-vessel CAD). The sensitivity of SPECT in patients with CAD was higher than ST depression (88% versus 28%, P = 0.001). The exercise was ...

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