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Article: Quantitative blood flow measurement of skeletal muscle using oxygen-15-water and PET
- Article from:
- The Journal of Nuclear Medicine
- Article date:
- February 1, 1997
- Author:
CopyrightCopyright Society of Nuclear Medicine Feb 1997. Provided by ProQuest LLC. (Hide copyright information)
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The aim of the present study was to evaluate quantitation of muscle blood flow using [^sup 15^O]H20 and PET. Methods: The autoradiographic (ARG) and the steady-state methods using PET were used to measure femoral muscle blood flow. A simulation study was performed to examine the errors due to contamination of radioactivity in the blood content in muscle tissue, statistical noise and delay and the dispersion of the input curve in the ARG method. Five separate paired muscle blood flow examinations were carried out for comparison of the ARG and the steady-state techniques, including measurement of muscle blood volume in each subject. To obtain the normal range for resting muscle blood flow, ...
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