Article: Disulfiram and low nickel diet in the management of hand eczema: A clinical study

Hand eczema is a common and distressing dermatological condition. It is a chronic and recurring problem. The exact prevalence rate of hand eczema in India is not known. However, in the West, the prevalence rate is found to be 8%[1] among the adults in the general population and the 1-year prevalence is up to 10%[2] in the age group of 16-19 years. Hand eczema is caused by various exogenous and endogenous factors; one of the exogenous factors is ingested nickel. It has been observed that ingested nickel can provoke or aggravate hand eczema in a sensitized individual and such sensitive individual develops flare of existing hand eczema after taking nickel orally.[3]

Nickel sensitivity is ...

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