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Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats

INTRODUCTION

Although herbal medicines have long been used effectively in treating many diseases in Asian communities and throughout the world, the mechanism of most of the herbals used have not been defined. Many traditional plant treatments for diabetes are also used, but most of the evidence for their beneficial effects is anecdotal.[1] Fenugreek, onion and garlic were reported to have a hypoglycemic effect.[2],[3],[4],[5] Although there are suggestions about the mechanism of action of plants, the exact mechanism is unclear. Plants may act on blood glucose through different mechanisms, some of them may have insulin-like substances,[6] some may inhibit insulinas activity,[7] and others ...

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