Article: Part one, general considerations

The species barrier has been crossed by an as yet unidentified Infectious agent. Science is slowly elucidating the facts, but gaps in our knowledge make the assessment and reduction of risks a daunting task. To put further discussion into context, we begin with a brief overview of issues and concerns related to TSE diseases.

We are in the midst of an epidemic of fear," said James Mason, director of the Centers for Disease Control and Prevention, in 1985, referring to then-emerging AIDS outbreaks. Fast forward a decade: "Deja vu all over again" (1). Same scenario, different clinical syndrome. Decades of research have resulted in a plethora of publications on transmissible spongiform ...

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