Article: Stock your emergency department with ice packs: a practical guide to therapeutic hypothermia for survivors of cardiac arrest

Prognosis after cardiac arrest is dismal, with an overall survival rate of less than 6%. Outcomes vary with cardiac arrest rhythm: less than 2% of patients with asystolic or pulseless electrical activity survive, compared with up to 33% of patients with ventricular fibrillation or pulseless ventricular tachycardia. Advanced cardiac life-support algorithms focus on early aggressive resuscitation; unfortunately, most patients who survive do sustain anoxic brain injury. About 60% of cardiac arrest survivors regain consciousness; of these, one-third experience irreversible cognitive disabilities.

Treatment options for anoxic brain injury traditionally have been limited to supportive care. ...

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