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Article: Use of acetaminophen, NSAIDs, and aspirin linked to increased risk of hypertension in men

Article from:
Formulary
Article date:
June 1, 2007
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Men who use acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), or aspirin are at an increased risk of developing hypertension compared with nonusers (P≤.05 for all comparisons), according to the results of a large, retrospective, easecontrolled study published in the Archives of Internal Medicine.

The patient cohort used in this study was a subset of the 51,529 male health professionals enrolled in the Health Professionals Follow-up Study. Patients were excluded if they had a baseline diagnosis of hypertension or were using an antihypertensive medication. The cohort of 16,031 participants (median age, 63 years; interquartile range. 57-71 years) was followed up for 4 years. ...

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