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Pharmacological MRI: a biomarker in CNS drug discovery and development?

Today, in the pursuit of new objectives in medical research, innovative concepts and methods are increasingly coming into use. Some of them, applied to the development of CNS-active drugs, are becoming part of our current knowledge. These new concepts, methods and applications are sometimes merged, giving rise to new entities, and whereas specialists are well acquainted with these entities, many potentially interested researchers remain largely unaware of their full potential and limitations. Pharmacological magnetic resonance imaging (phMRI) as a possible biomarker in CNS drug discovery and development is a case in point.

In this editorial, we invite interested readers to focus on some of ...

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