Article: Subclinical hypothyroidism in infertile women: The importance of continuous monitoring and the role of the thyrotropin-releasing hormone stimulation test

Abstract

The aim of our study was to assess the prevalence of subclinical hypothyroidism (SH) after administering a thyrotropin-releasing hormone (TRH) stimulation test among women with normal serum thyroid-stimulating hormone (TSH) levels and various causes of infertility. Eighty-seven infertile women (39 with ovulation disorders and 48 with other causes of infertility) had a TRH stimulation test on day 3-7 of their cycle. Exaggerated TSH response (> 30 mIU/1 at 20, 40 or 60 min) following intravenous injection of 400 µg TRH was defined as SH. The TRH test was performed 2-4 months after the first visit to the clinic. We found that the prevalence of SH was significantly higher among ...

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