Article: Cancer Vaccines: Asymptotically Approaching Product Approval

Cancer vaccines under development have proven safe and well-tolerated, but establishing efficacy remains a challenge.

ABSTRACT

The notion that the immune system can prevent the emergence and growth of cancer is a century old. Despite considerable evidence in animal models that "cancer vaccines" induce effective immunological responses against tumors, the development of efficacious vaccines to treat cancer in humans has been much slower and far less promising. In the past decade, however, several vaccine strategies have made considerable clinical advancement, renewing the interest and confidence that a human cancer vaccine will be successfully launched. This article highlights several ...

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