Article: Renal function in male rats concurrently exposed to nicotine & ethanol

Sir,

Concurrent alcohol and nicotine consumption commonly occur together1. Long-term alcohol intake produces serious harmful effects on renal function2. Nicotine, being vasoconstrictive, increases blood pressure, potentially altering renal function3.

The incidence of smoking among individuals who abuse alcohol and opiates, is about 90 per cent, although alcoholic individuals smoke more cigarettes than those who abuse other substances4. The interactions between components of tobacco smoke and drugs have been of much concern and the subject of many investigations5. Although some workers investigated the influence of ethanol on renal function6 and nicotine on renal parameters5, very little ...

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