Article: In vitro lactose fermentation by human colonic bacteria is modified by Lactobacillus acidophilus supplementation

In Vitro Lactose Fermentation by Human Colonic Bacteria Is Modified by Lactobacillus acidophilus Supplementation1,2,3 Tianan Jiang4 and Dennis A. Savaiano5

ABSTRACT Adaptation of the colonic flora to lactose may contribute to lactose digestion in lactose maldigesters, and supplementation with Lactobacillus acidophilus may modify colonic fermentation of lactose and short-chain fatty acid production. We evaluated the capability of colonic bacteria to ferment lactose and the ability of L. acidophilus to modify lactose fermentation by the colonic microflora in vitro. An anaerobic continuous culture was established and inoculated with fresh samples of human feces. Lactose infusion was ...

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