Article: Vitamin C supplementation does not modify bone mineral content or mineral absoprtion in growing pigs

Vitamin C Supplementation Does Not Modify Bone Mineral Content or Mineral Absorption in Growing Pigs1,2

A. Pointillart,3 I. Denis, C. Colin and H. Lacroix

Laboratoire de Nutrition et Securite Alimentaire, INRA, 78352 Jouy en Josas cedex, France

ABSTRACT We have demonstrated that alkaline phosphatase activity and collagen synthesis are dose-dependently stimulated by ascorbic acid in differentiated pig osteoblasts. In this study we further examined the relationship between ascorbic acid and bone metabolism by feeding young pigs large amounts of ascorbic acid. Three groups of seven 47-d-old pigs were given no ascorbic acid supplement (control), 500 (500 AA) or 1000 (1000 AA) mg ascorbic ...

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