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Article: Vitamin C supplementation does not modify bone mineral content or mineral absoprtion in growing pigs
- Article from:
- The Journal of Nutrition
- Article date:
- August 1, 1997
- Author:
CopyrightCopyright American Institute of Nutrition Aug 1997. Provided by ProQuest LLC. (Hide copyright information)
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Vitamin C Supplementation Does Not Modify Bone Mineral Content or Mineral Absorption in Growing Pigs1,2
A. Pointillart,3 I. Denis, C. Colin and H. Lacroix
Laboratoire de Nutrition et Securite Alimentaire, INRA, 78352 Jouy en Josas cedex, France
ABSTRACT We have demonstrated that alkaline phosphatase activity and collagen synthesis are dose-dependently stimulated by ascorbic acid in differentiated pig osteoblasts. In this study we further examined the relationship between ascorbic acid and bone metabolism by feeding young pigs large amounts of ascorbic acid. Three groups of seven 47-d-old pigs were given no ascorbic acid supplement (control), 500 (500 AA) or 1000 (1000 AA) mg ascorbic ...