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Article: Darier's sign
- Article from:
- Indian Journal of Dermatology, Venereology and Leprology
- Article date:
- September 1, 2007
- Author:
CopyrightCopyright Medknow Publications Sep/Oct 2007. Provided by ProQuest LLC. (Hide copyright information)
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Introduction
Darier's sign refers to the urtication and erythematous halo that are produced in response to rubbing or scratching of lesions of cutaneous mastocytosis.
Darier's sign is named after the French dermatologist Ferdinand-Jean Darier who first described it. The first description of mastocytosis was made by Nettleship and Tayface=+Superscript; [1
]face=-Superscript; in 1869, and in 1878, Sangster coined the term urticaria pigmentosa.face=+Superscript; [2
]face=-Superscript;
Method of Elicitation
In classical Darier's sign, gentle rubbing or stroking of the lesions, is followed by local itching, erythema and weal formation within 2-5min. This may persist from 30min to several hours. ...