Article: Influence of PPAR-¿ Agonist Fenofibrate on Insulin Sensitivity and Selected Adipose Tissue-derived Hormones in Obese Women with Type 2 Diabetes

Article: PPAR-[alpha] and Insulin Sensitivity
Physiological Research;  March 1, 2006 ;     700+ words ... ... the role of PPAR-α ... regulation of insulin sensitivity. In most ... possible role of PPAR-α ... regulation of insulin sensitivity in humans ... potential of PPAR-α ... to improve insulin sensitivity The prevalence ...

Article: PPAR alpha/gamma activation enhances insulin ...
Diabetes Week;  April 28, 2003 ;     700+ words ... ... Dual PPAR alpha/gamma ... enhanced insulin sensitivity and glycemic ... Improvement of insulin sensitivity caused by the dual PPAR-alpha ... Metabolism (Dual PPAR alpha/gamma ... improvement of insulin sensitivity and glycemic ...

Article: PPAR-alpha deficiency does not alter insulin ...
Diabetes Week;  May 31, 2004 ;     700+ words ... ... not alter insulin sensitivity in mice maintained ... receptor (PPAR)-alpha ... parameters of insulin sensitivity was comparable in PPAR-alpha KO ... show that PPAR-alpha deficiency ... not alter insulin sensitivity in mice fed ...

Article: Macrophage PPAR[gamma] is required for normal skeletal ...
Journal of Clinical Investigation;  June 1, 2007 ;     700+ words ...PPAR[gamma] is required for fat cell development ... Unexpectedly, we found that inactivation of PPAR[gamma] in macrophages results in the development ... signaling in adipose tissue, muscle, and liver. PPAR[gamma]-deficient macrophages secreted ...

Article: PGC-1[alpha]-induced improvements in skeletal muscle metabolism ...
Applied Physiology, Nutrition, and Metabolism;  June 1, 2009 ;     700+ words ... ... proliferator-activated receptor [gamma] (PPAR[gamma]) coactivator 1[alpha] (PGC ... regulating genes involved in lipid metabolism. PPAR[gamma] activation was required to fully ... ultimately led to the identification of the PPAR[gamma] coactivator PGC-1 (Puigserver ...

Article: Hypotension, lipodystrophy, and insulin resistance in generalized ...
Journal of Clinical Investigation;  March 1, 2007 ;     700+ words ... ... 6-8). The PPAR[gamma]-agonist ... TZDs) increase insulin sensitivity, lower blood glucose ... 17) or liver insulin sensitivity only (18). Hepatic PPAR[gamma] is required to maintain insulin sensitivity, particularly ...

Article: Trans-10, Cis-12 Conjugated Linoleic Acid Antagonizes ...
The Journal of Nutrition;  March 1, 2008 ;     700+ words ... ... hypoglycemics that activate PPARγ, leading ... thereby enhancing insulin sensitivity. Natural ligands of PPARγ2 such ... reported to impair insulin sensitivity, possibly by decreasing ... the expression of PPARγ and many ...