Article: Systematic Review and Meta-analysis of Real-World Adherence to Drug Therapy for Osteoporosis

OBJECTIVE: To quantify the adherence of patients to drug therapy for osteoporosis in real-world settings via a systematic review and meta-analysis of observational studies.

METHODS: The PubMed and Cochrane databases were searched for English-language observational studies published from January 1,1990, to February 15, 2006, that assessed patient adherence to drug therapy for osteoporosis using the following medical subject headings and keywords: drug therapy, medication adherence, medication persistence, medication possession ratio, patient compliance, and osteoporosis. Studies were stratified into 3 groups: persistence (how long a patient continues therapy), compliance (how correctly, In ...

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