|
|
Article: Magnetic resonance spectroscopy study in basal ganglia of patients with myoclonic epilepsy with ragged-red fibers
- Article from:
- Neurology India
- Article date:
- October 1, 2007
- Author:
CopyrightCopyright Medknow Publications Oct-Dec 2007. Provided by ProQuest LLC. (Hide copyright information)
|
The brain magnetic resonance imaging (MRI) findings in patients with myoclonic epilepsy with ragged-red fibers (MERRF) disease were not specific. [1] The most common one was cerebral and cerebellar atrophy. [2] Some reports stated that the cerebral and cerebellar white matter may have low densities on CT and patchy T2 prolongation on MRI. However, in Kendall half the proven cases did not reveal any abnormality on neuroimage. [2] Basal ganglia of abnormal magnetic resonance spectroscopic (MRS) study may provide further information by looking into regional brain metabolic abnormalities and give a clue for early detection of mitochondrial disease. [3] Therefore we give a brief survey of MRS ...