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An overview of high-dose melphalan and stem cell transplantation in the treatment of AL amyloidosis
- Article from:
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Amyloid
- Article date:
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December 1, 2007
- Author:
- Sanchorawala, Vaishali; Seldin, David C
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Copyright informationCopyright Taylor & Francis Ltd. Dec 2007. Provided by ProQuest LLC. (Hide copyright information)
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Keywords: AL amyloidosis, treatment, stem cell transplantation, melphalan
Abbreviations: HDM/SCT= high-dose melphalan and stem cell transplantation; CR = hematologic complete response; FLC=serum free light chain concentration; TRM = treatment-related mortality
Abstract
AL amyloidosis is the most common form of systemic amyloidosis and is associated with an underlying plasma cell dyscrasia. This review outlines an overview of high-dose intravenous melphalan and stem cell transplantation in the treatment of AL amyloidosis. An algorithm of our recommendations for the treatment of AL amyloidosis is also outlined.
Introduction
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