Immunoglobulin D lambda multiple myeloma and amyloidosis with predominant soft tissue involvement

Keywords: IgD lambda myeloma, AL amyloidosis, amyloid arthropathy, mucocutaneous amyloidosis

Abbreviations: MM = multiple myeloma; IgD = immunoglobulin D

Abstract

Multiple myeloma (MM) is associated with amyloidosis in approximately 15% of the patients. The most frequent presenting signs of such an association are nephrotic syndrome, cardiomyopathy and peripheral neuropathy. Amyloid arthropathy is not a frequent feature. We report a patient with immunoglobulin D (IgD) lambda type MM with presenting symptoms related to mucocutaneous amyloidosis and also amyloid arthropathy. He had no clinical and laboratory involvement due to nephrotic syndrome or cardiomyopathy. IgD myeloma is a rare form ...

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