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Article: Skeletal PET with ^sup 18^F-Fluoride: Applying New Technology to an Old Tracer*
- Article from:
- The Journal of Nuclear Medicine
- Article date:
- January 1, 2008
- Author:
CopyrightCopyright Society of Nuclear Medicine Jan 2008. Provided by ProQuest LLC. (Hide copyright information)
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Although ^sup 18^F-labeled NaF was the first widely used agent for skeletal scintigraphy, it quickly fell into disuse after the introduction of ^sup 99m^Tc-labeled bone-imaging agents. Recent comparative studies have demonstrated that ^sup 18^F-fluoride PET is more accurate than ^sup 99m^Tc-diphosphonate SPECT for identifying both malignant and benign lesions of the skeleton. Combining ^sup 18^F-fluoride PET with other imaging, such as CT, can improve the specificity and overall accuracy of skeletal ^sup 18^F-fluoride PET and probably will become the routine clinical practice for ^sup 18^F-fluoride PET. Although ^sup 18^F-labeled NaF and ^sup 99m^Tc-diphosphonate have a similar patient ...
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... ... literature about new applications for ^sup 123^I, the pure [gamma]emitting isotope ... of only 13.6 hours. Among the many ^sup 123^I radiopharmaceuticals now compounded for routine or research uses are ^sup 123^l-fluoropropylcarbomethoxyiodophenyl ...
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