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Article: Ramelteon: A melatonin receptor agonist for the treatment of insomnia
- Article from:
- Journal of Postgraduate Medicine
- Article date:
- January 1, 2008
- Author:
CopyrightCopyright Medknow Publications Jan-Mar 2008. Provided by ProQuest LLC. (Hide copyright information)
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The management of insomnia involves search of specific medical causes and use of non-pharmacological and appropriate pharmacological treatment. [1] Benzodiazepine receptor agonists are the most commonly prescribed agents for insomnia, but they are associated with a higher risk of motorcycle accidents, falls and fractures, overdose and cognitive impairment, along with potential for abuse and dependence. [2] Treatment with ramelteon, a novel MT 1 and MT 2 melatonin receptor selective agonist does not appear to impair cognition or motor performance. Data from clinical studies suggest that ramelteon is not likely to cause abuse, physical dependence or withdrawal effects. [3],[4],[5],[6],[7] ...