Article: Possible Bupropion Interaction With Ropivacaine: Setting the Stage for Seizure?

Article: Effect of local anesthetics on monocyte receptor expression determined.
Drug Week;  October 1, 2004 ;     398 words ......com & NewsRx.net) -- The effects of local anesthetics on monocyte receptor expression have...characterized. It has been demonstrated that local anesthetics have several effects on the immune...infection; however, the effect of local anesthetics on monocyte surface receptor ...

Article: Enhancement of Proopiomelanocortin Gene Promoter Activity by Local Anesthetics in a Pituitary Cell Line
Regional Anesthesia and Pain Medicine;  January 1, 2007 ;     700+ words ......it is not known whether local anesthetics can directly affect the...expression. We hypothesized that local anesthetics may directly affect proopiomelanocortin...the presence or absence of local anesthetics (lidocaine, mepivacaine...

Article: Scavenging Nanoparticles: An Emerging Treatment for Local Anesthetic Toxicity
Regional Anesthesia and Pain Medicine;  July 1, 2005 ;     700+ words ......complication of local anesthetic use in regional...intravascular local anesthetic injection...intravenous local anesthetic injection...manifestations of local anesthetic toxicity range from local neurotoxic and...mechanisms whereby local anesthetics ...

Article: Disciplinary actions associated with the administration of local anesthetics against dentists and dental hygienists.
Journal of Dental Hygiene;  January 1, 2005 ;     700+ words ......ability of dental hygienists to provide local anesthetics for pain control and reduction of...hygiene regarding the administration of local anesthetics by dental hygienists. Some dentists...when dental hygienists administer local anesthetics. Results. Eighteen responses were...

Article: Local Anesthetics in Lipid-Depot Formulations-Neurotoxicity in Relation to Duration of Effect in a Rat Model
Regional Anesthesia and Pain Medicine;  September 1, 2006 ;     700+ words ......number of lipid-depot formulations of local anesthetics in relation to their duration of...suggest that depot formulations of local anesthetics with advantageous pharmaceutical...Key Words: Bupivacaine, Lidocaine, Local anesthetics, Neurotoxicity, Sciatic-nerve block...

Article: Local and regional anesthesia techniques, Part 1: Overview and five simple techniques
Veterinary Medicine;  January 1, 2009 ;     700+ words ......provided with combinations of local anesthetics, opioids, and alpha2 agonists...analgesia in veterinary patients - local anesthetics, opioids, and alpha., agonists. Local anesthetic drugs Local anesthetics are weak bases that are poorly...

Article: Pathophysiology of Peripheral Nerve Injury During Regional Anesthesia
Regional Anesthesia and Pain Medicine;  September 1, 2008 ;     700+ words ......Exposure of peripheral nerves to local anesthetics may result in axonal damage...contribute to neuronal damage by local anesthetics, but elevated intracellular...Neuropathy, Regional anesthesia, Local anesthetics. Although the great majority...sensitivity. Furthermore, local ...

Article: Local Anesthetics Have Different Mechanisms and Sites of Action at Recombinant 5-HT^sub 3^ Receptors
Regional Anesthesia and Pain Medicine;  November 1, 2007 ;     700+ words ......voltage-dependent sodium channels, the action of local anesthetics at 5-hydroxytryptamine-3 (5-HT^sub...may be clinically relevant. Because local anesthetics have different clinical properties...by investigating the effects of 4 local anesthetics on recombinant wild-type and 4 ...

Article: Recent findings from University of Virginia highlight research in life sciences.
Biotech Week;  March 11, 2009 ;     335 words ...Purpose of review Local anesthetics are drugs which have many...promising areas where systemic local anesthetics are being implemented, scientists...conducted with the use of systemic local anesthetics when considering their cost...

Article: Antidepressants as Long-Acting Local Anesthetics
Regional Anesthesia and Pain Medicine;  May 1, 2004 ;     700+ words ......investigated, slow-release preparations of local anesthetics have been developed, and new, very-long-ac...could now rightfully be considered as local anesthetics. In a variety of models, these compounds...times greater than that of classical local anesthetics. Thus, they might ...

Article: Extended-Duration Analgesia: Update on Microspheres and Liposomes
Regional Anesthesia and Pain Medicine;  May 1, 2005 ;     700+ words ...Local anesthetics delivered peripherally or to the...the opioid-sparing effects of local anesthetics are associated with reduced opioid-relat...benefits of even the longest-acting local anesthetics are limited to <6 hours when...

Article: US FTC: Merger of Zeneca and Astra, two significant suppliers of pharmaceuticals, cleared with conditions.
M2 Presswire;  March 26, 1999 ;     700+ words ......in the U.S. market for long-acting local anesthetics. Under the settlement agreement...important drug market. Long-acting local anesthetics are products used by physicians to...the course of a medical procedure. Local anesthetics have no sedative effect, leaving...

Article: Which Actions of Local Anesthetics Are Relevant to the Medical Care of Humans?
Regional Anesthesia and Pain Medicine;  November 1, 2007 ;     700+ words ......length of nerve will be bound by local anesthetics to prevent impulse conduction.1 Consequently...anesthetic toxicity? When we discover that local anesthetics have a concentration-dependent action...fundamental problem is that clinical local anesthetics have limited potency at ...

Article: Local Anesthetics: Helpful Science, but Don't Forget the Basic Clinical Safety Steps
Regional Anesthesia and Pain Medicine;  November 1, 2005 ;     700+ words ......and treatment of the toxicity of local anesthetics since the tragic reports in 1979...then newer, more potent, aminoamide local anesthetics may also be potentially more toxic...problems of systemic toxicity of local anesthetics,3 finer nuances remain to be developed...