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Article: [beta]2-nAChR Availability in PTSD

Article from:
The Journal of Nuclear Medicine
Article date:
March 1, 2008
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In an article e-published on January 11 ahead of print in the International Journal of Neuropsychopharmacology, Czermak et al. from the Yale University School of Medicine (New Haven, CT) and the Veterans Affairs Connecticut Healthcare System (West Haven) reported on a study of nicotinic acetylcholine receptors containing β2 subunits (β2-nAChRs) in symptomatic patients with posttraumatic stress disorder (PTSD). The study included never-smoking PTSD patients, neversmoking healthy volunteers, and a subgroup of participants with a history of smoking. ^sup 123^I-5-IA-85380 SPECT was used to assess the availability of β2-nAChRs in the mesiotemporal ...

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