Magazine article from our research archive:
|
|
Spatial Distribution of Maxi-Anion Channel on Cardiomyocytes Detected by Smart-Patch Technique
- Article from:
-
Biophysical Journal
- Article date:
-
March 1, 2008
- Author:
- Dutta, Amal K; Korchev, Yuri E; Shevchuk, Andrew I; Hayashi, Seiji; Okada, Yasunobu; Sabirov, Ravshan Z
|
Copyright informationCopyright Biophysical Society Mar 1, 2008. Provided by ProQuest LLC. (Hide copyright information)
|
ABSTRACT
Spatial distribution of maxi-anion channels in rat cardiomyocytes were studied by applying the recently developed patch clamp technique under scanning ion conductance microscopy, called the "smart-patch" technique. In primary-cultured neonatal cells, the channel was found to be unevenly distributed over the cell surface with significantly lower channel activity in cellular extensions compared with the other parts. Local ATP release, detected using a PC12 cell-based biosensor technique, also exhibited a similar pattern. The maxi-anion channel activity could not be detected in freshly isolated adult cardiomyocytes by the conventional patch-clamp with 2-Mohm pipettes. However, when ...
|
Wide Nanoscopic Pore of Maxi-Anion Channel Suits its Function as an...
Biophysical Journal;
September 1, 2004 ;
Sabirov, Ravshan Z; Okada, Yasunobu;
787 words
......function of the maxi-anion channel as a conductive...pathway for ATP release requires...nanoscopic maxi-anion channel pore provides...pathway for ATP release in cell-to-ce...swelling-induced ATP release. Also, both...swelling-induced ...
|
|
The Effects of Short-Term Training on Platelet Functions and Total...
Physiological Research;
March 1, 2006 ;
Ficicilar, H; Zergeroglu, A M; Ersoz, G; Erdogan, A; Et al;
787 words
......on in vitro platelet aggregation and ATP release. Blood samples were collected from the...group. Platelet aggregation and platelet ATP release were evaluated by impedance and bioluminescence...was higher and ADP-induced platelet ATP release was lower in the short-term training...
|
|
Human Plasma ATP Concentration
Clinical Chemistry;
February 1, 2007 ;
Gorman, Mark W; Feigl, Eric O; Buffington, Charles W;
787 words
......plasma ATP concentration is lower if ATP release from formed blood elements is inhibited...both stop ATP catabolism and inhibit ATP release from blood elements. The stabilizing...When precautions are taken to inhibit ATP release from blood elements during sample preparation...
|
|
Estrogen replacement therapy and atherosclerosis.
American Family Physician;
August 1, 1993 ;
358 words
......aggregation and adenosine triphosphate (ATP) release were observed three months after the...decrease in both platelet aggregation and ATP release than that seen after estrogen only treatment...changes in platelet aggregation and ATP release. The authors conclude that platelet...
|
|
SENSING TOOL HELPS STUDY OF CYSTIC FIBROSIS
US Fed News Service, Including US State News;
March 30, 2006 ;
787 words
......investigate adenosine triphosphate (ATP) release and its role in cystic fibrosis. The...the multi-scanning biosensors to study ATP release at the surface of live epithelial cells...Before you can identify what triggers the ATP release, we must be able to quantitatively measure...
|
|
Evidence of a Novel Cell Signaling Role for Extracellular Adenosine...
Plant Cell;
October 1, 2004 ;
Jeter, Collene R; Tang, Wenqiang; Henaff, Elizabeth; Butterfield, Tim; Roux, Stanley J;
787 words
......exocytosis of ATP packaged in synaptic vesicles, as well as ATP release occurring via unknown anion channels (Sauer et al., 2000...resistance transporter activity (Boyum and Guidotti, 1997). ATP release sites have been observed to colocalize with ecto-ATPase enzymatic...
|
|
Extracellular ATP Functions as an Endogenous External Metabolite...
Plant Cell;
November 1, 2005 ;
Chivasa, Stephen; Ndimba, Bongani K; Simon, William J; Lindsey, Keith; Slabas, Antoni R;
787 words
......Yang et al., 1994). Touch stimulation and osmotic stress elicit increased ATP release from Arabidopsis (Jeter et al., 2004), suggesting conservation of ATP release in response to mechanical stimulation between plants and animals. Neuronal...
|
|
Use of Helper Enzymes for ADP Removal in Infrared Spectroscopic...
Biophysical Journal;
May 1, 2005 ;
Liu, Man; Karjalainen, Eeva-Liisa; Barth, Andreas;
787 words
......generated after ATP hydrolysis by ATPase, which enables repeat of ATP-release experiments several times with the same sample without interference...which inhibits the binding of ATP released in subsequent ATP-release experiments. This makes it unsuitable to repeat the experiment...
|
|
The role of ATP in rosacea development
Dermatology Times;
February 1, 2008 ;
Guttman, Cheryl;
605 words
......a role in the pathogenesis of rosacea. "We know the sympathetic nerves are stimulated during stress, and so we wondered if ATP release might play a role in the observed link between stress and the onset or exacerbation of rosacea and some other skin diseases...
|
|
On the Inside
Plant Physiology;
November 1, 2006 ;
Minorsky, Peter V;
787 words
......eATP were closely correlated with regions of active growth and cell expansion. Various calcium-regulating drugs revealed that ATP release is a Ca^sup 2+^-dependent process and may occur through vesicular fusion, an important step in the polar growth of actively...
|
|
RESOURCE CENTRE | NEW PRODUCTS
Functional Ingredients;
March 1, 2008 ;
Anonymous;
787 words
......Fuser has a large quantity of RNA (instead of protein or carbohydrates), which assists cellular communication. RNA causes ATP release, thus enabling better mental focus. +1 770 375 8020 www.fuserbar.com High-protein fruit bars In November, Abbott launched...
|
|
Extracellular ATP in Plants. Visualization, Localization, and Analysis of...
Plant Physiology;
November 1, 2006 ;
Kim, Sung-Yong; Sivaguru, Mayandi; Stacey, Gary;
787 words
......regions of active growth and cell expansion. Pharmacological compounds known to alter cytoplasmic calcium levels revealed that ATP release is a calcium-dependent process and may occur through vesicular fusion, an important step in the polar growth of actively growing...
|
|
Model of the outer membrane potential generation by the inner membrane of...
Biophysical Journal;
February 1, 2002 ;
Lemeshko, Victor V;
787 words
......voltage-dependent anion channels localized beyond the contact sites. This mechanism suggests that the outer membrane potential may arrest ATP release through the outer membrane beyond the contact sites, thus tightly coordinating mitochondrial metabolism and aerobic glycolysis...
|
|
PILOT PEN 2006: Pool play may be in Pilot Pen's future
New Haven Register;
August 28, 2006 ;
Jim Fuller;
626 words
......it being a staple of the tour in 2008 and 2009, assuming all goes well next year. Why make this drastic move? The official ATP release states "the format increases spectators' chances of seeing their favorite stars, as one loss in a round-robin pool does not...
|
|
Cells' secrets revealed.(a Georgia research team is using a modified...
Sensors Magazine;
July 1, 2006 ;
vL Henkel, Stephanie;
315 words
......with Douglas Eaton at Emory University's School of Physiology, the Georgia Tech investigators used the modified AFM to study ATP release at the surface of live epithelial cells, those that cover most glands and organs in the body. In addition to Mizaikoff and...
|
See all results.
Or, try our
Advanced Search.
|