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A study of allergen-specific IgE antibodies in Indian patients of atopic dermatitis

Introduction

Atopic Dermatitis (AD) is a chronic, relapsing, extremely pruritic dermatitis in which there is a propensity to increased production of IgE to environmental allergens. AD, along with bronchial asthma, allergic rhinitis and allergic conjunctivitis is included in atopic group of diseases. Recent prevalence surveys suggest that about 10-20% of children in developed countries suffer from AD. [1],[2],[3],[4],[5],[6],[7] AD has a complex etiology that encompasses immunologic responses, susceptibility genes, environmental triggers, and compromised skin-barrier function.

It is difficult to define AD because of its intermittent nature, varying clinical picture with age, and the ...

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