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Childhood sclerodermatomyositis with generalized morphea

Introduction

The term overlap syndrome (OS) may be used when patients exhibit clinical features of two or more classical connective tissue diseases (CTDs). Such patients may not only meet diagnostic criteria for one disease but also have atypical manifestation or findings suggestive of a second CTD. These include mixed connective tissue disease (MCTD), sclerodermatomyositis (SDM) and antisynthetase antibody syndrome (ASS). Systemic sclerosis combined with DM is the most frequently seen overlap syndrome and is called sclerodermatomyositis or scleromyositis. It has been mainly described in adults with a few cases of childhood SDM. Blaszczyk et al. [1] and Vandergheynst et al. [2] have ...

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