Article: A transient lesion occupying the entire corpus callosum associated with neonatal hypoglycemia

A one-year-old girl, the product of an uncomplicated vaginal delivery presented on day 3 of life with complaints of poor sucking. She was hypotonic on examination and ultimately developed seizures. Laboratory examination revealed marked hypoglycemia (2 mg/dL). Rest of the investigations including serum electrolytes was normal but serum osmolality was not done at that time. Her symptoms resolved with glucose loading. The etiology of her hypoglycemia was unclear. Computerized tomography of the brain demonstrated bilateral low-density lesions in the occipital lobes on the 4th postnatal day. On postnatal day 17, diffusion weighted magnetic resonance imaging (MRI) of the brain disclosed a high ...

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