Article: Q Fever: Epidemiology, Diagnosis, and Treatment

On completion of this article, you should be able to (1) describe recent trends in the epidemiology of Q fever, including the increasing incidence in the United States; (2) identify the variable presentations of Q fever and the proper use of serology in confirming the diagnosis; and (3) interpret serologic follow-up after acute Q fever to determine when further work-up and treatment for infective endocarditis are necessary.

Q fever, a zoonosis caused by Coxiella burnetil, is seen throughout the world. Recent reports suggest that its incidence in the United States is increasing, with more than 30 cases reported in the US military. The disease has many acute and chronic manifestations. ...

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