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Article: Coronary Artery Aneurysm: A Review and Hypothesis Regarding Etiology
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- May 1, 2008
- Author:
CopyrightCopyright College of American Pathologists May 2008. Provided by ProQuest LLC. (Hide copyright information)
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Context.-Coronary artery aneurysm is an uncommon condition that can be a cause of death when it thromboses or ruptures. It is always associated with destruction of the tunica media, usually associated with atherosclerosis, and commonly associated with chronic inflammation.
Objective.-To review the pathology, epidemiologic and clinical features, and pathophysiology of coronary artery aneurysm, particularly new research results, drawing out implications for the understanding, diagnosis, and treatment of this condition.
Data Sources.-Pertinent literature and illustrative cases at our institution.
Conclusions.-Inflammation spilling over into the tunica media from the tunica intima may link ...