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Patterns of Molecular Evolution in Caenorhabditis Preclude Ancient Origins of Selfing
- Article from:
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Genetics
- Article date:
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April 1, 2008
- Author:
- Cutter, Asher D; Wasmuth, James D; Washington, Nicole L
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Copyright informationCopyright Genetics Society of America Apr 2008. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
The evolution of self-fertilization can mediate pronounced changes in genomes as a by-product of a drastic reduction in effective population size and the concomitant accumulation of slightly deleterious mutations by genetic drift. In the nematode genus Caenorhabditis, a highly selfing lifestyle has evolved twice independently, thus permitting an opportunity to test for the effects of mode of reproduction on patterns of molecular evolution on a genomic scale. Here we contrast rates of nucleotide substitution and codon usage bias among thousands of orthologous groups of genes in six species of Caenorhabditis, including the classic model organism Caenorhabditis elegans. Despite ...
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Michigan Academician;
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242 words
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Human Biology;
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Thuillet, A-C; Bataillon, T; Poirier, S; Santoni, S; David, J L;
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Singh, Nadia D; Davis, Jerel C; Petrov, Dmitri A;
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Genetics;
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Meuwissen, Theo H E; Goddard, Mike E;
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