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The Effects of Recombination Rate on the Distribution and Abundance of Transposable Elements
- Article from:
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Genetics
- Article date:
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April 1, 2008
- Author:
- Dolgin, Elie S; Charlesworth, Brian
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Copyright informationCopyright Genetics Society of America Apr 2008. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
Transposable elements (TEs) often accumulate in regions of the genome with suppressed recombination. But it is unclear whether this pattern reflects a reduction in the efficacy of selection against deleterious insertions or a relaxation of ectopic recombination. Discriminating between these two hypotheses has been difficult, because no formal model has investigated the effects of recombination under the deleterious insertion model. Here we take a simulation-based approach to analyze this scenario and determine the conditions under which element accumulation is expected in low recombination regions. We show that TEs become fixed as a result of Hill-Robertson effects in the form of ...
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